Sensitivity of a questionnaire for data collection on venous thrombosis.

In clinical research, questionnaires are an important tool available for population and large family studies to gather information on a patient’s medical history. In 1989, we described a large kindred of FrenchCanadian descent with an 8-fold increased risk of venous thrombosis due to the 3363C insertion in the protein C gene [1]. We developed a questionnaire for use in this family to assess general information on social status, current health, current medication use and medical history, and detailed information on risk factors for venous thrombosis and a history of